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. Author manuscript; available in PMC: 2023 Jul 16.
Published in final edited form as: Nat Cardiovasc Res. 2023 Jan 16;2:144–158. doi: 10.1038/s44161-022-00206-6

Extended Data Figure 3. Epidemiological causal inference analysis for CHIP on incident peripheral artery disease in the UK Biobank.

Extended Data Figure 3.

a) Propensity scores by CHIP and Large CHIP status in the UKB (n=37,657). b) Propensity score adjustment and stabilized inverse probability treatment weighting (IPTW) for the CHIP and Large CHIP association with incident PAD in the UKB. Error bars are centered at the HR and show the 95% CI for estimates. CHIP = clonal hematopoiesis of indeterminate potential; VAF = variant allele fraction; PAD = peripheral artery disease