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. 2022 Dec 8;22(7):758–776. doi: 10.1080/15384101.2022.2154543

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Figure 7. — CircSCN8A exerts a tumor-suppressive activity in NSCLC by sponging miR-1290.(a-e) A549 and SK-MES-1 cells were transfected with miR-NC+vector, miR-1290+vector, miR-NC+circSCN8A, or miR-1290+circscn8a. (a and b) Cell proliferation ability was assessed by using CCK-8 and colony formation assays. (c) Wound healing assay of cell migration. (d and e) Transwell assay of cell migration and invasion. (f) Western blot assay of E-cadherin, N-cadherin, and vimentin. Scale bar: 50 μm. *P <0.05, **P <0.01, ***P <0.001.