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. 2023 Mar 2;19(1):2177066. doi: 10.1080/21645515.2023.2177066

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© 2023 Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, NJ, USA. Published with license by Taylor & Francis Group, LLC.

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Figure 3. — Serotype-specific OPA GMTs at baseline (Day 1) and 30 days post-vaccination (Day 30) with V114 or PCV13 by number of baseline risk factors.

Pre-defined risk factors include chronic liver, lung, and heart disease, diabetes mellitus, tobacco use, and alcohol consumption. The within-group 95% CIs were obtained by exponentiating the CIs of the mean of the natural log values based on the t-distribution. n is the number of participants randomized and vaccinated with PCV. ^†Additional serotypes in V114. CI: confidence interval; GMT: geometric mean titer (1/dilution); OPA: opsonophagocytic activity; PCV: pneumococcal conjugate vaccine; PCV13: 13-valent pneumococcal conjugate vaccine; V114: 15-valent pneumococcal conjugate vaccine.