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. 2023 Mar 2;19(1):2177066. doi: 10.1080/21645515.2023.2177066

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© 2023 Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, NJ, USA. Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 5. — Serotype-specific OPA GMTs at 30 days post-vaccination with V114 by specific single risk conditions.

The within-group 95% CIs were obtained by exponentiating the CIs of the mean of the natural log values based on the t-distribution. n is the number of participants contributing to the analysis. Participants with chronic liver disease and alcohol consumption were grouped together due to low numbers in each individual group. CI: confidence interval; GMT: geometric mean titer (1/dilution); OPA: opsonophagocytic activity; PCV: pneumococcal conjugate vaccine; V114: 15-valent pneumococcal conjugate vaccine.