Table 4.
Incidence of adverse events.
| Grade |
|||
|---|---|---|---|
| 1–2 | 3 | ≥4 | |
| N (%) | N (%) | N (%) | |
| TRAEs | |||
| Leukopenia | 37(55.2) | 9(13.4) | 0(0) |
| Thrombocytopenia | 31(46.3) | 7(10.4) | 1(1.5) |
| Increased ALT or AST | 19(28.4) | 3(4.5) | 0(0) |
| Fatigue | 20(29.9) | 4(6.0) | 0(0) |
| Nausea or emesis | 10(14.9) | 1(1.5) | 0(0) |
| Colitisor Diarrhea | 17(25.4) | 6(9.0) | 0(0) |
| irAEs | |||
| Rash | 2(3.0) | 3(4.5) | 2(3.0) |
| Pneumonitis | 0(0) | 1(1.5) | 0(0) |
| Hypothyroidism | 9(13.4) | 0(0) | 0(0) |
| Hyperthyroidism | 4(6.0) | 0(0) | 0(0) |
| Myositis | 0(0) | 2(3.0) | 1(1.5) |
| Hepatitis | 0(0) | 2(3.0) | 0(0) |
| Others | 15(22.4) | 0(0) | 0(0) |
Abbreviations: TRAEs, treatment-related adverse events; irAEs, immune-related adverse events; ALT, alanine aminotransferase; AST, aspartate aminotransferase.