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. Author manuscript; available in PMC: 2024 Jan 17.
Published in final edited form as: Anal Chem. 2023 Jan 2;95(2):659–667. doi: 10.1021/acs.analchem.2c02042

Figure 3. Determining the optimal type of magnetic bead for bead-based multi-omics sample preparation.

Figure 3.

Fold change in intensity of common metabolites, lipid classes (summed), and peptide GRAVY score between each bead type and no beads (MTBE extraction) from human plasma. Each bar represents the average of three technical replicates. Bead types and venders are referenced in the text. The abbreviations used for the metabolites are as follows: cytidine 5’-diphosphocholine (CDP-choline), lysine (Lys), glycine (Gly), arginine (Arg), ornithine (Orn), 2-aminoadipic acid (2-AAA), aspartic acid (Asp), glutamic acid (Glu), glutathione (GSH), serine (Ser), nicotinamide (NAM), pantothenic acid (PA), and uridine monophosphate (UMP).