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. 2022 Oct 13;77(4):1228–1240. doi: 10.1002/hep.32746

FIGURE 3.

FIGURE 3

JAK2 inhibition with pacritinib treatment reduces contraction and migration of rodent and immortalized human‐derived HSCs. (A) Quantification and representative images of contraction assay at 72 h, and (B) scratch assay quantification and representative pictures (B) at 24 h. Results are expressed as the mean ± standard deviation; # p < 0.1. *p < 0.05, **p < 0.01, and ***p < 0.001. HSC, hepatic stellate cell; JAK2, Janus kinase 2; SM22Cre+‐Jak2f/f, floxed‐Jak2 knockout mice with smooth muscle protein 22 Cre‐promotor; NT, nontreated; Pac, pacritinib; WT, wild type.