FIG. 3.
Sum1-1, but not Sum1, interacts with Orc5 in the two-hybrid assay. (A) Filter assay for lacZ expression of strain L40 transformed with a plasmid containing lexA-ORC5 (pTT93) and plasmids containing GAD (pGAD424), GAD-SUM1-1 (pRH02), or GAD-SUM1 (pRH01). (B) Western analysis of extracts from strains used in panel A probed with anti-GAD antibody. The significance of the faint upper band in panel B, which is seen only with GAD-Sum1 and GAD-Sum1-1 fusion proteins, is unknown. β-gal, β-galactosidase.