Table 1.
Patient Characteristics
| Characteristics | All n = 41 |
|---|---|
| Demographics | |
| Race/ethnicity | |
| Hispanic white | 9 (22%) |
| Non-Hispanic white | 29 (71%) |
| Other/unknown | 3 (7%) |
| Female, n (%) | 30 (73) |
| Age (years) | 55 ± 11 (32–77) |
| BMI (kg/m2) | 34.4 ± 5.7 (24.4–47.4) |
| Past medical history | |
| Diabetes, n (%) | 12 (29.3) |
| Hypertension, n (%) | 20 (48.8) |
| Hyperlipidemia, n (%) | 19 (46.3) |
| Laboratory | |
| ALT | 62.1 ± 49.8 (10–217) |
| Creatinine | 0.83 ± 0.15 |
| GFRa (CKD-EPI) | 88.3 ± 18.4 (56–127) |
| Insulin concentration | 186.4 ± 256.0 (0.8–1110.2) |
| HOMA-IR | 8.9 ± 11.6 (0.1–51.6) |
| Pathology | |
| Steatosis, n (%) | |
| <2 | 20 (49) |
| ≥2 | 21 (51) |
| Activityb | |
| <4 | 25 (61) |
| ≥4 | 16 (39) |
| Fibrosis | |
| <3 | 25 (61) |
| ≥3 | 16 (39) |
a
CKD-EPI calculation of GFR.
b
NASH activity (range 0–5) was calculated as a sum of lobular inflammation (0–3), and ballooning degeneration (0–2).
BMI, body mass index; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; GFR, glomerular filtration rate; HOMA-IR, homeostatic model assessment for insulin resistance; NASH, nonalcoholic steatohepatitis.