. 2021 Nov 8;19(9):491–497. doi: 10.1089/met.2021.0055

Table 3.

Association Between Nonalcoholic Steatohepatitis Activity and Fibroblast Growth Factor 21 Based on Linear Regressions

Outcome	Model 1^a		Model 2^b		Model 3^c		Model 4^d
Outcome	Fold change (95% CI)	P	Fold change (95% CI)	P	Fold change (95% CI)	P	Fold change (95% CI)	P
FGF21	0.56 (0.32–0.98)	0.04	0.48 (0.26–0.91)	0.03	0.50 (0.26–0.95)	0.04	0.54 (0.30–0.96)	0.04

Values in bold denote P < 0.05.

For each outcome, the fold changes of outcome at high NASH activity with respect to low activity were reported.

^{^a}

Model 1 unadjusted.

^{^b}

Model 2 adjusts for age, gender, and BMI.

^{^c}

Model 3 adjusts for age, gender, BMI, and GFR.

^{^d}

Model 4 adjusts for age, gender, BMI, GFR, and HOMA-IR.

FGF, fibroblast growth factor; FGF21, fibroblast growth factor 21.