Skip to main content
. 2019 May 28;36(12):1923–1934. doi: 10.1089/neu.2018.6101

FIG. 2.

FIG. 2.

In female and male rats, spinal cord injury (SCI) disrupted rhythmic fecal output, body mass, and food intake. (A, B) Uninjured and pre-injury rats produced 5–25% of fecal pellets (A) and mass (B) during the inactive phase. SCI caused significant disruption at acute times, with up to 50% of pellets and mass being produced in the inactive phase (gray dotted line; representing random inactive-active fecal output). Abnormal fecal output rhythms recovered by 14–42 days post-injury (dpi). (C) After SCI, rats had reduced body mass compared with shams for 4 dpi (females) and 21 dpi (males). (D) Changes in body mass were accompanied by altered food intake: Compared with sham rats, female rats with SCI increased food intake at 7 and 14 dpi; male SCI rats showed reduced food intake at 2 dpi, then increased food intake at 7 and 14 dpi. *p < 0.05 for sham vs. SCI at that time-point. Color image is available online.