. Author manuscript; available in PMC: 2023 Mar 20.

Published in final edited form as: Diabetes Care. 2008 Mar 3;31(6):1195–1200. doi: 10.2337/dc07-1971

Table 3—

HLA class II allele frequencies in KPD subgroups compared with ethnicity-specific population control subjects

	HLA class II allele frequencies in autoantibody-positive (A+) KPD subgroups compared with ethnicity-specific population control subjects
	Ethnic-specific control subjects			A+β− KPD			A+β+ KPD
Allele	Caucasian	African American	Hispanic	Caucasian	African American	Hispanic	Caucasian	African American	Hispanic
n	414	69	78	4	19	9	3	5	6
Susceptibility
DRB1*03	80 (19)	12 (17)	5 (6)	2 (50)	6 (32)	6 (67)^*	1 (33)	2 (40)	3 (50)^*
DRB1*04	154 (37)	7 (10)	41 (53)	3 (75)	7 (37)^*	7 (78)	2 (67)	0	4 (67)
DQB1*02	130 (31)	10 (14)	14 (18)	2 (50)	14 (74)^*	5 (56)^*	2 (67)	2 (40)	3 (50)
DQB1*0302	59 (14)	4 (6)	33 (42)	3 (75)^*	5 (26)^*	7 (78)	2 (67)	0	2 (33)
Resistance
DQB10301 and 0303	258 (62)	38 (55)	67 (86)	2 (50)	8 (42)	2 (22)^*	2 (67)	2 (40)	4 (67)

	HLA class II allele frequencies in autoantibody-negative (A−) KPD subgroups compared with ethnicity-specific population control subjects
	Ethnic-specific control subjects			A−β− KPD			A−β+ KPD
Allele	Caucasian	African American	Hispanic	Caucasian	African American	Hispanic	Caucasian	African American	Hispanic
n	414	69	78	7	15	16	8	37	54
Susceptibility
DQB1*02	130 (31)	10 (14)	14 (18)	3 (43)	7 (47)^*	4 (25)	1 (13)	12 (32)^*	15 (28)
DQB1*0302	59 (14)	4 (6)	33 (42)	2 (29)	1 (7)	9 (56)	1 (13)	1 (3)	26 (48)
Resistance
DQB1*0602	64 (15)	7 (10)	6 (8)	0	1 (7)	1 (6)	1 (13)	14 (38)^*	5 (9)
DQB10301 and 0303	258 (62)	38 (55)	67 (86)	4 (57)	6 (40)	6 (38)^*	4 (50)	8 (22)^*	26 (48)^*
Unknown
DQB1*05	116 (28)	10 (14)	12 (15)	3 (43)	7 (47)^*	3 (19)	3 (38)	7 (19)	4 (7)
DQB1*06	203 (49)	19 (28)	23 (29)	2 (29)	2 (13)	2 (13)	4 (50)	11 (30)	3 (6)^*

Data are n (%).

P < 0.05 (KPD subgroup compared with ethnicity-specific control subjects).