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. Author manuscript; available in PMC: 2023 Mar 20.
Published in final edited form as: Nature. 2022 May 25;606(7914):557–564. doi: 10.1038/s41586-022-04739-5

Extended Data Fig. 5. Immunohistochemistry of TR proteins in reactive astrocytes after SCI.

Extended Data Fig. 5.

a. Newly identified TRs co-localized by IHC in reactive astrocytes in thoracic spinal cord (T9-T-10) after SCI (see also Extended data figures 3,4). b. Summary of all (newly identified and previously published) astrocyte reactivity TRs after LPS treatment identified here by at least two experimental procedures, either prediction from DEGs by TREA, or prediction based on significant change in motif access determined by ATACseq or by IHC or by all three. c. Nine examples of previously published TRs co-localized by IHC in reactive astrocytes in thoracic spinal cord (T9-T-10) after SCI show that these exhibit similar staining patterns to TRs newly identified here. Each immunohistochemical evaluation was repeated at least three times with similar results.