Obesity-associated remodeling of the myeloid-cell immune compartment of adipose tissue in mice and humans. VAMs/PVMs and ncMos are abundant in the lean adipose tissue, whereas the balance tips towards an enrichment of LAMs, IMs and Mos during obesity progression in mice as well as humans. Abbreviations: LAM, lipid associated macrophage; PVM, perivascular macrophage124; IM, inflammatory macrophage 206; Mos, Monocyte subpopulations Mo1 and Mo2; ncMos, non-canonical monocytes 203.