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Schematic of the necroptosis execution model. The diagram is color coded to highlight the processes involved in formation of complex I, complex II, complex IIa, complex IIb, and the necrosome. Arrows are labeled with “RN” or “RN-M,”, where N and M correspond to reaction indices in the model. In many cases (but not all; see text), “RN-M” denotes a set of reversible reactions, with N the index of the forward reaction and M the index of the reverse. Created with BioRender.com.
