Table 3.
Comparison of radiologic features and laboratory findings
| FNEC | NEC | Z/χ2 | p | |
|---|---|---|---|---|
| (n = 40) | (n = 166) | |||
| NEC age onset (d) | 16.5 (4.0, 29.8) | 13 (7.25) | − 0.096 | 0.923 |
| Distention at NEC onset (n%) | 28 (70.0) | 93 (56.0) | − 1.608 | 0.108 |
| Bloody stools at NEC onset (n%) | 9 (22.5) | 59 (35.5) | − 1.571 | 0.116 |
| Fever at NEC onset (n%) | 4 (10.0) | 5 (3.0) | − 1.936 | 0.053 |
| Vomit at NEC onset (n%) | 7 (17.5) | 16 (9.6) | − 1.414 | 0.157 |
| Assisted ventilation at NEC onset intubated (n%) | 28 (70.0) | 45 (27.1) | − 5.079 | < 0.001 |
| Shock at NEC onset (n%) | 15 (37.5) | 23 (13.9) | − 3.453 | 0.001 |
| Pneumatosis at NEC onset (n%) | 14 (35.0) | 34 (20.5) | − 1.945 | 0.052 |
| Portal venous gas at NEC onset (n%) | 5 (12.5) | 11 (6.6) | − 1.243 | 0.214 |
| Pneumoperitoneum at NEC onset (n%) | 3 (7.5) | 5 (3.0) | − 1.316 | 0.188 |
| ANC before NEC onset (109/L) | 4.69 (2.34, 6.34) | 4.42 (2.69, 6.14) | − 0.022 | 0.982 |
| ALC before NEC onset (109/L) | 2.91 (1.48,4.32) | 3.63 (2.52, 4.64) | − 1.879 | 0.6 |
| AMC before NEC onset (109/L) | 0.78 (0.45, 1.66) | 0.95 (0.61, 1.28) | − 0.629 | 0.529 |
| AEC before NEC onset (109/L) | 0.37 (0.12, 0.61) | 0.43 (0.20, 0.74) | − 1.309 | 0.191 |
| PLT before NEC onset (109/L) | 231 (147, 327) | 267 (183, 342) | − 1.172 | 0.241 |
| CRP before NEC onset (mg/dL) | 0.30 (0.20, 0.72) | 0.50 (0.21, 1.00) | − 1.573 | 0.116 |
| Lac before NEC onset (mmol/L) | 0.8 (0.5, 1.1) | 0.9 (0.6, 1.2) | − 1.365 | 0.172 |
| ANC at NEC onset (109/L) | 2.61 (1.82, 4.80) | 4.56 (3.09, 8.26) | − 3.855 | < 0.001 |
| ALC at NEC onset (109/L) | 1.10 (0.71, 1.94) | 2.00 (1.14, 3.66) | − 3.41 | 0.001 |
| AMC at NEC onset (109/L) | 0.29 (0.09, 0.55) | 0.7 (0.378, 0.99) | − 4.614 | < 0.001 |
| AEC at NEC onset (109/L) | 0.05 (0.01, 0.13) | 0.13 (0.04, 0.32) | − 3.176 | 0.001 |
| PLT at NEC onset (109/L) | 166 (113, 223) | 220 (145, 295) | − 2.615 | 0.009 |
| CRP at NEC onset (mg/dL) | 43.77 (9.10, 82.59) | 20.99 (3.44, 67.91) | − 1.925 | 0.051 |
| Lac at NEC onset (mmol/L) | 1.7 (1.2, 3.4) | 1.3 (0.9, 1.8) | − 2.887 | 0.004 |
| ANC day 1 after NEC (109/L) | 3.23 (1.97, 5.12) | 5.30 (3.31, 8.30) | − 3.99 | 0.001 |
| ALC day 1 after NEC (109/L) | 1.37 (0.82, 2.56) | 2.76 (1.72, 4.11) | − 4.249 | < 0.001 |
| AMC day 1 after NEC (109/L) | 0.40 (0.21, 0.74) | 0.94 (0.64, 1.39) | − 5.109 | < 0.001 |
| AEC day 1 after NEC (109/L) | 0.20 (0.06, 0.61) | 0.25 (0.06, 0.61) | − 0.782 | 0.434 |
| PLT day 1 after NEC (109/L) | 108 (56, 226) | 199 (123, 259) | − 3.392 | 0.001 |
| CRP day 1 after NEC (mg/dL) | 62.50 (26.57, 106.36) | 45.98 (11.53, 87.53) | − 1.799 | 0.072 |
| Lac day 1 after NEC (mg/dL) | 2.4 (1.4, 4.5) | 1.5 (1.2, 1.8) | − 3.486 | < 0.001 |
ANC absolute neutrophil counts, ALC absolute lymphocyte counts, AMC absolute monocyte counts, AEC absolute eosinophil counts, PLT platelet, Lac lactate