FIGURE 2.
Mean blood lipid mediator log concentrations (pg/ul) among participants from the Mass General Brigham Biobank with rheumatoid arthritis cases and their matched controls without rheumatoid arthritis, taking and not taking fish oil supplements
Unadjusted analyses. Abbreviations: ARA, Arachidonic acid, EPA, eicosapentaenoic acid; DHA, docosahexaenoic acid; LTB4, Leukotriene B4; LXA4, Lipoxin A4; LXB4, Lipoxin B4; MaR1–2, Maresin 1–2; PGD2, Prostaglandin D2; PGE2, Prostaglandin E2; PGF2a, Prostaglandin F2 alpha; TXB2, Thromboxane B2; PD1, Protectin D1; RA, rheumatoid arthritis; RvD1, RvD2, RvD3, RvD4, RvD5, and RvD6, D-series resolvins; RvE1, RvE2, RvE3, and RvE4, E-series resolvins; 14-HDHA, 14-hydroxy-docosahexaenoic acid; 15-HEPE, 15-hydroxyeicosapentaenoic acid; 17-HDHA, 17-hydroxy-docosahexaenoic acid; 18-HEPE, 18-hydroxyeicosapentaenoic acid.
* p value < 0.05
** FDR < 0.05