TABLE 1.
Characteristics of participants with rheumatoid arthritis and matched controls without rheumatoid arthritis from the Mass General Brigham Biobank
| Parameter | Rheumatoid Arthritis Cases (n=52) | Non-Rheumatoid Arthritis Matched Controls (n=52) | P value* |
|---|---|---|---|
| Matching Factors | |||
| Age at blood draw (mean, SD) | 50.0 (7.37) | 49.5 (7.35) | 0.73 |
| Female, n (%) | 44 (84.6) | 44 (84.6) | 1.00 |
| Race | 0.27 | ||
| -White, n (%) | 47 (90.4) | 48 (92.3) | |
| -Non-White, n (%) | 5 (9.6) | 2 (3.9) | |
| Smoking Status | 0.35 | ||
| -Never, n (%) | 33 (63.5) | 34 (65.4) | |
| -Past, n (%) | 17 (32.7) | 12 (23.1) | |
| -Current, n (%) | 2 (3.9) | 4 (7.7) | |
| Other Covariates | |||
| Body mass index kg/m2 (mean, SD) | 29.8 (10.42) | 26.0 (4.54) | 0.02 |
| Taking a statin medication, n (%) | 6 (11.5) | 4 (7.7) | 0.74 |
| Characteristics of Rheumatoid Arthritis cases | |||
| Rheumatoid factor positive, n (%) | 26 (50.0) | ||
| Anti-CCP positive, n (%) | 15 (28.9) | ||
| Elevated ESR or CRP, n (%) | 24 (46.2) | ||
| Taking steroid, n (%) | 8 (15.4) | ||
| Taking immunosuppressant, n (%) | 43 (82.7) | ||
Chi squared test for categorical values and t-test for continuous variables. N: number; SD: standard deviation; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; anti-CCP: anti-cyclic citrullinated peptide; Race data missing in 2 matched controls without RA. Smoking status missing in 2 matched controls without RA ESR or CCRP missing in 3 patients with RA