Figure 2.

Immunofluorescence analysis of collagen I in control (Co) and pEDS fibroblasts. Control fibroblasts exhibit a high abundant collagen network with strong fiber-like staining in the extracellular space. In patient fibroblasts, the quantity of the collagen network is strongly reduced and the fiber-like staining is weaker and thinner. This is a representative figure of four independent experiments. Scale = 20 µm.