TABLE 1.
Data sources and description of suicidal behaviour, psychiatric, behavioural and socioeconomic GWAS datasets.
| Phenotype/Reference | Ancestry | Consortium/Source | Sample size | Variable | #Cases | #Controls | Web links/URLs |
|---|---|---|---|---|---|---|---|
| Suicidal behaviour | |||||||
| Suicidal ideation | |||||||
| Recent thoughts of suicide or self-harm | EUR | United Kingdom Biobank/Neale lab | 125,844 | Continuous | NA | NA | https://www.nealelab.is/uk-biobank |
| Thought life not worth living (TLNWL) | EUR | United Kingdom Biobank/Neale lab | 117,291 | Continuous | NA | NA | https://www.nealelab.is/uk-biobank |
| Thoughts of death during worst depression | EUR | United Kingdom Biobank/Neale lab | 62,648 | Binary | 32,630 | 30,018 | https://www.nealelab.is/uk-biobank |
| Ever contemplated self-harm (ECSH) | EUR | United Kingdom Biobank/Neale lab | 117,610 | Continuous | NA | NA | https://www.nealelab.is/uk-biobank |
| Suicide attempt | |||||||
| Attempted suicide (Erlangsen et al., 2018) (SA) | EUR | iPSYCH | 50,264 | Binary | 6,024 | 44,240 | https://ipsych.dk/en/research/downloads/ |
| Ever attempted suicide | EUR | United Kingdom Biobank/Neale lab | 4,933 | Binary | 2.658 | 2.275 | https://www.nealelab.is/uk-biobank |
| Self-harm | |||||||
| Ever self-harmed (ESH) | EUR | United Kingdom Biobank/Neale lab | 117,733 | Binary | 5,099 | 112,634 | https://www.nealelab.is/uk-biobank |
| Seeking mental health services | EUR | United Kingdom Biobank/Neale lab | 117,733 | Binary | 1,693 | 116,040 | https://www.nealelab.is/uk-biobank |
| Completed suicide | |||||||
| Suicide death (Otsuka et al., 2019) | EAS | 14,795 | Binary | 746 | 14,049 | https://humandbs.biosciencedbc.jp/hum0196-v1 | |
| Psychiatric traits | |||||||
| Schizophrenia (Pardinas et al., 2018) | EUR | Clozuk + PGC2 | 105,318 | Binary | 40,675 | 64,643 | https://walters.psycm.cf.ac.uk/ |
| Schizophrenia (Lam et al., 2019) | EAS | PGC | 58,140 | Binary | 22,778 | 35,362 | https://www.med.unc.edu/pgc/download-results/ |
| Bipolar Disorder (Stahl et al., 2019) | EUR | PGC2 BD | 51,710 | Binary | 20,352 | 31,358 | https://www.med.unc.edu/pgc/download-results/ |
| MDD (Giankopolou et al., 2021) | EAS | PGC | 194,548 | Binary | 15,771 | 178,777 | https://www.med.unc.edu/pgc/download-results/ |
| MDD (Wray et al., 2018) | EUR | PGC | 480,359 | Binary | 135,458 | 344,901 | https://www.med.unc.edu/pgc/download-results/ |
| Anorexia Nervosa (Duncan et al., 2017) | EUR | PGC | 14,477 | Binary | 3,495 | 10,982 | https://www.med.unc.edu/pgc/download-results/ |
| PTSD (Duncan et al., 2018) | EUR | PGC | 9,954 | Binary | 2,489 | 7,465 | https://www.med.unc.edu/pgc/download-results/ |
| ADHD (Demontis et al., 2018) | EUR | PGC | 53,293 | Binary | 19,099 | 34,194 | https://www.med.unc.edu/pgc/download-results/ |
| Alcohol use disorder (Walters et al., 2018) | EUR | PGC | 38,686 | Binary | 10,206 | 28,480 | https://www.med.unc.edu/pgc/download-results/ |
| Insomnia (Jansen et al., 2019) | EUR | United Kingdom Biobank | 386,533 | Binary | 109,402 | 277,131 | https://ctg.cncr.nl/software/summary_statistics |
| Behavioural traits | |||||||
| Drinks per week (Liu et al., 2019) | EUR | GSCAN | 941,280 | Continuous | NA | NA | https://conservancy.umn.edu/handle/11299/201564 |
| Drinks per week (Matoba et al., 2020) | EA | GWAS catalogue | 58,610 | Continuous | NA | NA | https://www.ebi.ac.uk/gwas/downloads/summary-statistics/ |
| Cigarettes per day (Liu et al., 2019) | EUR | GSCAN | 337,334 | Continuous | NA | NA | https://conservancy.umn.edu/handle/11299/201564 |
| Cigarettes per day (Matoba et al., 2019) | EA | BBJ | 72,655 | Continuous | NA | NA | http://jenger.riken.jp/en/result |
| Smoking (ever vs never) Kanai et al., 2021 | EA | BBJ | 176,166 | Binary | 88,277 | 87,889 | https://pheweb.jp/pheno/Smoking_Ever_Never |
| Anthropometric traits | |||||||
| Body mass index (Locke et al., 2015) | EUR | GIANT consortium | 322,154 | Continuous | NA | NA | https://www.nealelab.is/uk-biobank |
| Body mass index (Sakau & Kanai et al., 2021) | EA | BBJ | 163,835 | Continuous | NA | NA | https://pheweb.jp/pheno/BMI |
| Socioeconomic traits | |||||||
| Household Income (Hill et al., 2016) | EUR | United Kingdom Biobank | 112,151 | Continuous | NA | NA | http://www.ccace.ed.ac.uk/node/335 |
| Education in years (Okbay et al., 2016) | EUR | SSGAC | 293,723 | Continuous | NA | NA | https://thessgac.com/papers/ |