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. 2023 Mar 7;14:1134325. doi: 10.3389/fendo.2023.1134325

Figure 8.

Figure 8

Validation of diagnostic markers in animal experiments. (A) The levels of body weight, blood glucose, serum creatinine, blood urea nitrogen, and urine albumin-creatinine ratio in mice. (B) Hematoxylin and eosin (H&E), periodic acid Schiff (PAS), Masson staining of mouse kidney. (C) mRNA expression levels of four diagnostic markers in kidney tissue. (D) Expression levels of markers in blood and urine. (E) Representative immunohistochemical staining of the kidneys for the four markers. ns, P < 0.05.