Figure 2.

Leptin-mediated recruitment of LepR^LH neurons during feeding

(A) Longitudinal registration of neurons imaged across experiments.

(B) Representative Ca²⁺ traces. Scale bar, x = 25 s, y = 0.5 SD.

(C and D) Food-elicited responses of leptin-activated neurons following acute food restriction.

(C) Local fit. Scale bar, x = 10 s, y = 0.4 SD.

(D) Ca²⁺ signal before and after entry into food location. n = 13 neurons, 5 mice. ^∗p = 0.027, paired Wilcoxon signed-rank test.

Data shown are mean ± SEM. ^∗p < 0.05, ^∗∗∗p < 0.001.

See also Figure S4.