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. 2023 Mar 7;13:1120103. doi: 10.3389/fonc.2023.1120103

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Copyright © 2023 Gu, Li, Yao, Dong, Gan, Zhou, Wang and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of hub DEGs. (A) DEGs are shown by the volcano plot. Red dots represent genes that are upregulated in the resistance group (logFC > 2 and P.value < 0.01), and green dots represent genes that are downregulated (logFC < 2 and P.value < 0.01). (B) The heatmap shows the top 30 up-regulated and top 30 down-regulated genes in the drug resistance group. Red means genes up-regulated and blue means genes down-regulated. (C) 45 hub DEGs PPI network.