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. Author manuscript; available in PMC: 2023 Jun 1.
Published in final edited form as: Continuum (Minneap Minn). 2022 Jun 1;28(3):676–701. doi: 10.1212/CON.0000000000001082

FIGURE 2-1.

FIGURE 2-1

Imaging of the patient in CASE 2-1. Amyloid imaging showed diffuse cortical and subcortical signal consistent with Alzheimer disease (not shown). A, Flortaucipir F 18 positron emission tomography (PET) shows intense tau ligand uptake in the medial and lateral temporal and parietal cortices and milder uptake in the frontal lobes. Flortaucipir F 18 PET images show the standardized uptake value ratio (SUVR) of tau, where warmer colors (yellow, red, and orange) indicate more tau uptake. B, Sagittal volumetric MRI presented in three-dimensional space shows bilateral medial temporal/hippocampal, parietal, and, to a lesser extent, frontal atrophy (bottom panel); warmer colors (yellow, red, and orange) indicate areas of greater gray matter atrophy.