Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Mar 7;14:1095487. doi: 10.3389/fphar.2023.1095487

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2023 Zeng, Huang, Zhang, Lv, Cheng, Zou, Han, Wang, Gong and Peng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Dapagliflozin reduced the expression of renal fibrosis-related markers in 0.2% adenine diet-fed mice. (A, B) Western blot showing the expression of Collagen 1, α-SMA, and vimentin in the renal tissue of each group. (C) Real time PCR showing the expression of col1a1, col3a1, FN, Vimentin, α-SMA, and MMP7 in the renal tissue of each group. Values are means ± SD. **p < 0.01 adenine diet group compared with the control group; ***p < 0.001 adenine diet group compared with the control group; ^# p < 0.01 dapagliflozin treatment group compared with the adenine diet group; ^## p < 0.01 dapagliflozin treatment group compared with the adenine diet group; ^### p < 0.001 dapagliflozin treatment group compared with the adenine diet group.