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. 2023 Mar 7;14:1095487. doi: 10.3389/fphar.2023.1095487

FIGURE 3.

FIGURE 3

Analysis of renal transcriptome in 0.2% adenine diet-induced renal fibrosis mice. (A) Volcano plot of gene expression difference between the control and 0.2% adenine diet groups. (B) Volcano plot of gene expression difference between the 0.2% adenine diet and 10 mg/kg dapagliflozin treatment groups. (C) Heatmap of gene expression difference among the control, 0.2% adenine diet, and dapagliflozin 10 mg/kg groups. (D) GO analysis of differentially expressed genes. (E, F) KEGG analysis of differentially expressed genes. N: control diet M: 0.2% adenine diet D 0.2% adenine diet + dapagliflozin (10 mg/kg).