TABLE 1.

Demographic and clinical characteristics of PPAs groups

Variable	PPA	avPPA	svPPA	p value*
Number	103	73	30	‐
Age at evaluation, years	65.4 ± 8.5	66.1 ± 8.5	63.6 ± 8.4	.17
Sex, female%	58.3	59.0	57.0	.83**
Age at onset, years	62.9 ± 8.7	63.6 ± 8.5	61.1 ± 8.9	.18
Education, years	9.7 ± 4.3	9.5 ± 4.3	10.3 ± 4.4	.41
Scanner type, % (A/B/C)	23.3/24.3/52.4	19.2/26.0/54.8	33.3/20.0/46.7	.30**
Clinical assessment at evaluation
CDR plus NACC SOB	6.0 ± 4.3	6.2 ± 4.5	5.6 ± 3.9	.57
MMSE	17.8 ± 8.3	16.8 ± 8.4	20.3 ± 7.4	.05
Short story	5.4 ± 4.4	5.4 ± 4.7	5.4 ± 4.0	1.00
Fluency, letter	14.7 ± 10.5	13.1 ± 9.9	18.3 ± 11.0	.03
Fluency, semantic	17.8 ± 11.4	18.2 ± 11.5	17.1 ± 11.2	.69
Token test	22.8 ± 9.3	21.6 ± 10.2	25.3 ± 6.8	.12
Rey complex figure, copy	23.4 ± 11.8	20.9 ± 12.3	28.9 ± 8.1	.001
Rey complex figure, recall	9.4 ± 6.6	9.5 ± 6.6	9.1 ± 6.8	.79
Trail making test, part A	151.1 ± 144.3	173.6 ± 146.0	97.0 ± 126.8	.02
Trail making test, part B	374.1 ± 161.1	411.1 ± 144.5	282.9 ± 166.3	.001
FBI, A	11.4 ± 6.7	11.3 ± 6.8	11.5 ± 6.5	.93
FBI, B	2.9 ± 3.2	2.1 ± 2.5	4.9 ± 3.8	.001
FBI, AB	14.3 ± 8.5	13.4 ± 8.1	16.4 ± 9.0	.11

Note: Neuropsychological scores are corrected for age and education, according to Italian normative data. Scanner type: A = 1.5 T Symphony, B = 1.5 T Avanto, C = 3 T Skyra. Bold values indicate p < 0.05.

Abbreviations: avPPA, nonfluent variant PPA; CDR plus NACC FTLD SOB, CDR dementia staging instrument plus behaviour and language domains from the National Alzheimer's Coordinating Center and Frontotemporal lobar degeneration modules—sum of boxes; FBI, frontal behavioural Inventory; MMSE, Mini‐Mental State Examination; PPA, primary progressive aphasia; svPPA, semantic variant PPA.

^*Student‐t test, unless otherwise specified.

^**Chi‐square test.