FIGURE 2.

Changes in clinical measures following Serial Ketamine Infusion. TRD patients showed significant improvements in overall depressed mood measured using HDRS, and anhedonia measured using SHAPS, following treatment. HDRS scores can range from 0 to 52 with higher scores indicating more severe depression, whereas SHAPS scores can range from 14 to 56 with lower scores indicating more severe anhedonia. Bar graphs show the mean scores and confidence intervals in the TRD group at baseline and post treatment, with p‐values from paired t‐tests labeled above. HDRS, Hamilton Depression Rating Scale; SHAPS, Snaith Hamilton Pleasure Scale; TRD, treatment resistant depression