Extended Data Figure 6.

Extended analyses of heritability enrichment in murine brain cell types. a, Correlation plot of p-value enrichment scores (FDR-corrected) for each cell type across different scDRS settings: A) default parameters (Methods) B) MAGMA gene z-score > 2.5, C) control gene set size of 2,000, D) control gene set size of 500, E) input expression dataset at the single-cell level (versus pseudocells), F) adjust for cell type proportions. b, Adjusted −log10 p-value enrichment scores for each cell type, grouped and colored by main region, for an extended set of GWAS-measured traits. c, Dot plot of the expression of key cortical pyramidal cell type markers within the eight isocortical clusters that were significantly enriched for schizophrenia heritability.