Table 2:
Stability of TranNet.
| Main | Alternative | Selected-predictors | Overlap | Jaccard Index | HG p-value | |
|---|---|---|---|---|---|---|
|
| ||||||
| BRCA | 9309 | 8172 | 279 | 228 | 0.8 | ≈ 0.0 |
| LUAD | 8691 | 7225 | 347 | 282 | 0.805 | ≈ 0.0 |
| LUSC | 9965 | 8635 | 398 | 317 | 0.79 | ≈ 0.0 |
| PRAD | 6399 | 4464 | 127 | 73 | 0.57 | 8.7e-125 |
| LIHC | 7514 | 5806 | 300 | 215 | 0.711 | 3.5e-322 |
Overlap in the selected predictors based on the networks constructed form two different selection of tumor genes. Main set is described in Table 4 in Section 6 and the Alternative set was selected with a different threshold as described in Section 3.3. We selected the same number of top predictors from each list based on the number of optimal predictors for the Main set. Overlap reports the number of common predictors, Jaccard Index: Jaccard Index similarity between the two sets of the highest scoring predictors and HG p-value is hyper-geometric p value for the enrichment of the predictors obtained with the Alternative set in the Main set.