Table 5.
Topological analysis results by degree—the first 20 proteins
| Gene names | Annotation | Closeness centrality | Degree |
|---|---|---|---|
| NTRK1 | Neurotrophic receptor tyrosine kinase 1 | 0.582762 | 218 |
| MCM2 | Minichromosome maintenance complex component 2 | 0.574324 | 210 |
| CUL3 | Cullin 3 | 0.557638 | 197 |
| NPM1 | Nucleophosmin | 0.555556 | 181 |
| FN1 | Fibronectin 1 | 0.555037 | 188 |
| HNRNPU | Heterogeneous nuclear ribonucleoprotein U | 0.5494 | 170 |
| ESR1 | Estrogen receptor 1 | 0.537975 | 167 |
| CDK2 | Cyclin dependent kinase 2 | 0.537975 | 154 |
| RPS11 | Ribosomal protein S11 | 0.534591 | 171 |
| RPS3A | Ribosomal protein S3A | 0.534111 | 148 |
| ITGA4 | Integrin subunit alpha 4 | 0.533632 | 164 |
| RPS3 | Ribosomal protein S3 | 0.533632 | 150 |
| CAND1 | Cullin associated and neddylation Dissociated 1 | 0.533154 | 165 |
| RPS4X | Ribosomal protein S4, X-linked | 0.530303 | 144 |
| COPS5 | COP9 signalosome subunit 5 | 0.524691 | 148 |
| RPS14 | Ribosomal protein S14 | 0.524691 | 146 |
| RPS16 | Ribosomal protein S16 | 0.524229 | 143 |
| VCAM1 | Vascular cell adhesion molecule 1 | 0.523307 | 146 |
| CUL1 | Cullin 1 | 0.519197 | 153 |
| ICAM1 | Intercellular adhesion molecule 1 | 0.510292 | 161 |