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Experimental timeline and changes in ovarian morphology and function in SD rats. A Experimental timeline. After the POI model was established by VCD injection, seven days after the first treatment, MSC transplantation was performed by two injections of PMSCs. Estrogen and progesterone treatment was used as a positive control. B experimental grouping. C Ovarian size. D Body weight change. E Ovarian weight. F Ovarian index. G Estrous cycle was measured by exfoliated vaginal cell staining
