Calculated β-NTP levels (a), intracellular pH, pHi (b), IVF (c), and iADC (d) in the HFBR cell culture as a function of time after the onset of ischemia. β-NTP levels are normalized to preischemia values. Diffusion times (Δ) used in the three different iADC experiments are indicated in the insert of (d). A significant difference between the postischemia and preischemia iADC is observed at all diffusion times (P < 0.005, Student’s paired t-test). Error bars in (d) represent error in the fit of data to a single exponential decay.