Table 3.
Clinical and echocardiographic characteristics of the phenotype-negative population
| Total LVH- (N = 84) | Sarc LVH- (N = 56) | GLA LVH- (N = 28) | P-value* | |
|---|---|---|---|---|
| Demographic characteristics | ||||
| ȃAge (years) | 39 ± 15 | 37 ± 15 | 40 ± 15 | 0.337 |
| ȃFemale (n,%) | 57 (68) | 38 (68) | 19 (68) | 1.000 |
| ȃHypertension (n,%) | 15 (18) | 9 (16) | 6 (21) | 0.546 |
| Echocardiographic characteristics | ||||
| ȃLV mass index (g/m2) | 80 (68–93) | 80 (69–92) | 78 (66–93) | 0.708 |
| ȃLVEDV index (mL/m2) | 49 (43–54) | 51 (45–56) | 47 (40–52) | 0.256 |
| ȃLVEF (%) | 63 ± 5 | 63 ± 6 | 64 ± 3 | 0.258 |
| ȃLV-GLS (%) | 21.8 (19.9–23.2) | 22.3 (20.6–23.7) | 20.2 (18.5–22.0) | 0.002 |
| ȃLAV index (mL/m2) | 28 (23–32) | 27 (23–33) | 29 (24–30) | 1.000 |
| ȃE/A ratio | 1.3 (1.1–1.7) | 1.3 (1.1–1.5) | 1.6 (1.3–1.9) | 0.013 |
| ȃE/E′ ratio | 7.1 (5.8–8.6) | 7.9 (6.0–9.3) | 6.3 (5.4–7.3) | 0.001 |
| ȃRVWT (mm) | 3.5 (3.0–4.0) | 3.5 (3.0–4.0) | 3.6 (3.2–4.0) | 0.747 |
| ȃRVEDA (cm2) | 16.4 (14.2–19.3) | 16.9 (14.1–19.3) | 15.1 (14.5–18.6) | 0.407 |
| ȃRVESA (cm2) | 8.3 (6.5–9.7) | 8.3 (6.5–9.7) | 8.0 (6.3–10.6) | 0.859 |
| ȃRAV index (ml/m2) | 14 (11–19) | 15 (11–19) | 14 (11–19) | 0.772 |
| ȃTAPSE (mm) | 24 ± 3 | 24 ± 3 | 23 ± 3 | 0.745 |
| ȃRVFAC (%) | 51 ± 6 | 51 ± 6 | 51 ± 6 | 0.817 |
| ȃRV S′ velocity (cm/s) | 13.4 ± 2.2 | 13.2 ± 3.0 | 13.5 ± 1.5 | 0.669 |
| ȃRV-GLS (%) | 24.9 (22.2–27.4) | 25.3 (22.9–28.0) | 23.5 (21.8–26.0) | 0.049 |
| ȃRV-FWS (%) | 29.2 (26.6–32.6) | 30.3 (27.5–33.4) | 26.6 (23.9–29.6) | <0.001 |
| ȃΔRV strain (%) | 4.3 (2.8–5.9) | 5.0 (3.3–7.0) | 2.9 (2.0–4.3) | <0.001 |
| ȃTR jet velocity (m/s) | 2.1 (2.0–2.3) | 2.1 (2.0–2.3) | 2.1 (2.0–2.4) | 0.989 |
Comparison of echocardiographic parameters was performed applying a Bonferroni correction. P values <0.0028 were considered statistically significant (18 comparisons) and are shown in bold type.
LAV, left atrial volume; LVEDV, LV end diastolic volume; RAV, right atrial volume; RVEDA, RV end-diastolic area; RVESA, RV end-systolic area; RVWT, RV wall thickness; TR, tricuspid regurgitation.