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. Author manuscript; available in PMC: 2023 Mar 21.
Published in final edited form as: Cancer Cytopathol. 2021 Feb 17;129(7):555–565. doi: 10.1002/cncy.22415

Table 4.

Clinical and Cytopathologic Characteristics of the False-Negative Cases (n=3).

Case Age/Sex Location Size (cm) Imaging Milan System Diagnostic Category Cytopathologic Findings Ancillary testing Follow-up Diagnosis
1 11/F Parotid 5.5 N/A Benign neoplasm Benign epithelial cells, lack of mucin, favor pleomorphic adenoma N/A MEC, low grade
2 12/F Submandibular 3.6 Left submandibular gland swelling with central hypodensity Nonneoplastic Few glandular cells, acute and chronic inflammatory cells and acinar groups N/A Involved by AML
3 18/M Parotid 7.3 Large enhancing right parotid gland mass with adjacent lymphadenopathy Nonneoplastic Abundant lymphocytes with variation in size and scattered tingible body macrophages, favor reactive intraparotid lymph node Flow cytometry analysis shows a polytypic population of lymphocytes NLPHL

Abbreviations: MEC, mucoepidermoid carcinoma; AML, acute myeloid leukemia; NLPHL, nodular lymphocyte predominant Hodgkin lymphoma.