Table 1.
Characteristics, vital parameters, and laboratory findings at admission of patients hospitalized with COVID-19.
| Non-survivors (n = 37) | Survivors (n = 86) | Total (n = 123) | p value | |
|---|---|---|---|---|
| Age | ||||
| ≤60 years, n (%) | 2 (5.4) | 36 (41.9) | 38 (30.9) | |
| 61–80 years, n (%) | 18 (48.6) | 35 (40.7) | 53 (43.1) | |
| ≥81 years, n (%) | 17 (45.9) | 15 (17.4) | 32 (26.0) | <0.0001 |
| Age, median [IQR] | 79 [71, 84] | 65 [53, 76] | 72 [59, 81] | <0.0001 |
| Sex | ||||
| Female, n (%) | 14 (37.8) | 36 (41.9) | 50 (40.7) | |
| Male, n (%) | 23 (62.2) | 50 (58.1) | 73 (59.3) | 0.83 |
| BMI, median [IQR]a | 27.4 [24.2, 31.1] | 27.9 [24.3, 31.5] | 27.9 [24.2, 31.2] | 0.70 |
| Hypertension, n (%) | 25 (67.6) | 34 (39.5) | 59 (48.0) | <0.01 |
| AMI and/or heart failure, n (%) | 3 (8.1) | 7 (8.1) | 10 (8.1) | 1.00 |
| Diabetes, n (%) | 15 (40.5) | 21 (24.4) | 36 (29.3) | 0.11 |
| COPD, n (%) | 4 (10.8) | 6 (7.0) | 10 (8.1) | 0.72 |
| Asthma, n (%) | 5 (13.5) | 10 (11.6) | 15 (12.2) | 1.00 |
| Infiltration on chest X-ray, n (%) | 34 (91.9) | 69 (80.2) | 103 (83.7) | 0.18 |
| Findings at admission | ||||
| respiratory rate (breaths/min) median [IQR]b | 22 [20, 30] | 20 [18, 26] | 21 [18, 28] | 0.15 |
| Oxygen saturation (%,) median [IQR] | 94 [91, 96] | 96 [94, 98] | 95 [93, 97] | 0.03 |
| Supplemental oxygen, n (%) | 22 (59.5) | 39 (45.3) | 61 (49.6) | 0.22 |
| Laboratory findings at admission | ||||
| Blood | ||||
| Lymphocytes × 109/L, median [IQR]c | 0.8 [0.6, 1.2] | 1.0 [0.8, 1.3] | 1.0 [0.7, 1.3] | 0.05 |
| Platelets × 109/L, median [IQR]c | 199 [166, 229] | 200 [173, 264] | 199 [168, 251] | 0.34 |
| Plasma | ||||
| Creatinine (µmol/L), median [IQR]c | 98 [85, 132] | 84 [69, 97] | 91 [75, 105] | <0.01 |
| ALT (U/L), median [IQR]c | 33 [28, 53] | 32 [22, 56] | 32 [24, 54] | 0.29 |
| LDH (U/L), median [IQR]d | 406 [312, 523] | 328 [237, 417] | 336 [251, 456] | 0.03 |
| CRP (mg/L), median [IQR]c | 110 [52, 183] | 95 [50, 146] | 98 [51, 153] | 0.22 |
| Serum | ||||
| Leptin (ng/mL), median [IQR] | 7.2 [3.7, 12.7] | 7.2 [3.8, 13.8] | 7.2 [3.8, 13.4] | 0.60 |
| Adiponectin (µg/mL), median [IQR] | 8.9 [3.9, 14.5] | 9.0 [6.0, 14.5] | 9.0 [5.7, 14.6] | 0.50 |
| Adiponectin/leptin ratio, median [IQR] | 1.5 [0.6, 2.4] | 1.0 [0.5, 2.8] | 1.1 [0.5, 2.6] | 0.89 |
a: BMI was missing for 17 subjects. b: respiratory rate was missing for 1 subject. c: lymphocytes, platelets, creatinine, ALT and CRP were missing for 18 subjects. d: LDH was missing for 24 subjects. ALT: alanine aminotransferase; AMI: acute myocardial infarction; BMI: body mass index; COPD: chronic obstructive pulmonary disease; CRP: C-reactive protein; LDH: lactate dehydrogenase.