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. 2023 Mar 16;10(1):e002211. doi: 10.1136/openhrt-2022-002211

Table 3.

Changes (mean change or change in proportion followed by 95% CI) in medical risk factors and cardioprotective medications in cardiovascular patients between IA, EOP and 6-month assessment

From IA to EOP From IA to 6 month follow-up
n IA EOP Change P value n IA 6 months Change P value
Blood pressure (mm Hg)
 Systolic blood pressure mean(SD) 62 137.1±15.7 117.6±8.1 −19.5 (−23.2, –15.8) <0.001 54 137.3±15.9 119.9±11.5 −17.7 (−22.5, –12.5) <0.001
 Diastolic blood pressure mean (SD) 62 75.9±9.3 73.7±8.3 −2.2 (−5.2, 0.9) 0.17 54 75.4±9.0 74.9±7.9 −0.5 (−3.5, 2.5) 0.76
 Blood pressure <130/80 (%) 62 24 68 44 (27, 60) <0.001 54 26 69 43 (25, 59) <0.001
LDL cholesterol
 LDL (mmol/l) mean (SD) 59 2.33±0.88 1.57±0.58 −0.76 (−0.98, –0.54) <0.001 37 2.18±0.76 1.71±0.74 0.47(−0.77, –0.16) 0.004
 LDL <1.4 mmol/L (%) 59 14 41 27 (14, 40) <0.001 37 14 41 27 (5, 49) 0.02
HbA1c <53* (%) 4 50 50 0 (−25, 25) 1.00 3 67 67 0 (−33, 33) 1.00
Cardioprotective medications
 Antiplatelets (%) 64 91 91 0 (−2, 2) 1.00 55 89 89 0 (−2, 2) 1.00
 Beta blockers (%) 64 67 66 −1 (−6, 3) 1.00 55 66 62 −4 (−10, 30) 0.50
 ACE inhibitors (%) 64 36 36 0 (−9, 9) 1.00 55 35 35 0 (−9, 9) 1.00
 ARB’s (%) 64 22 25 3 (−3, 9) 0.5 55 25 31 6 (−2, 13) 0.25
 Calcium channel blockers (%) 64 19 22 3 (−3, 9) 0.5 55 18 24 6 (−2, 2) 0.25
 Statins (%) 64 84 88 2 (−5, 11) 0.63 55 82 82 0 (−11, 11) 1.00
 Other lipid lowering medications (%) 64 5 17 12 (3, 22) 0.008 55 5 22 17 (5, 28) 0.004

*In those with known diabetes.

ARBs, angiotensin II receptor blockers; EOP, end of programme; HbA1c, glycosylated haemoglobin; IA, initial assessment; LDL, low-density lipoprotein.