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. 2023 Mar 22;1(1):100002. doi: 10.1016/j.chstcc.2023.100002

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© 2023 The Authors

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Scatterplot showing LV global strain (y-axis) vs LVEF (x-axis) at day 1 in 49 patients in whom both were measured. Strain measurements were converted to absolute values. The plot area was divided into four quadrants by the red lines, which indicate the lower threshold for normal strain and ejection fraction: normal strain and low LVEF (one patient), normal strain and normal LVEF (22 patients), abnormal strain and normal LVEF (15 patients), and abnormal strain and low LVEF (11 patients). Patients who died are represented by an ‘×,’ whereas patients who survived are represented by a dot. The percentage of patients who died was highest among those with abnormal strain and normal LVEF (53.33% mortality). The blue line is the best fit linear regression line representing the relationship between strain and LVEF. Patients with values beneath the linear regression line (indicating lower strain than predicted based on LVEF) showed higher mortality than those with values higher than the line (indicating higher strain than predicted based on LVEF). LV = left ventricle; LVEF = left ventricle ejection fraction.