Table 1.
Clinical and laboratory parameters.
| CON (n = 30) | Child-Pugh A (n = 32) | Child-Pugh B (n = 31) | Child-Pugh C (n = 27) | P-value | |
|---|---|---|---|---|---|
| Male gender, n (%) | 17 (57%) | 18 (56%) | 17 (55%) | 15 (56%) | 0.99 |
| Age (years) | 42.0 ± 10.9 | 42.9 ± 9.4 | 41.8 ± 7.6 | 41.5 ± 10.6 | 0.95 |
| BMI (kg/m²) | 23.4 ± 2.7 | 23.2 ± 2.9 | 23.2 ± 2.3 | 23.3 ± 3.0 | 0.99 |
| BSA (m²) | 1.7 ± 0.3 | 1.7 ± 0.4 | 1.7 ± 0.4 | 1.7 ± 0.4 | 0.99 |
| HR (bpm) | 68.8 ± 9.6 | 70.4 ± 9.6 | 71.7 ± 10.4 | 71.5 ± 6.6 | 0.62 |
| SBP (mm Hg) | 124.6 ± 9.2 | 121.8 ± 11.8 | 119.4 ± 9.4 | 119.9 ± 11.3 | 0.21 |
| DBP (mm Hg) | 77.0 ± 8.8 | 76.8 ± 8.8 | 75.2 ± 5.5 | 75.3 ± 7.1 | 0.71 |
| PP (mm Hg) | 47.6 ± 9.0 | 45.0 ± 10.7 | 44.2 ± 8.7 | 44.6 ± 9.9 | 0.52 |
| ALB (g/L) | 43.7 ± 6.7 | 39.4 ± 5.3* | 32.0 ± 8.4*,** | 22.9 ± 6.1*,**,*** | <0.001 |
| TBil (µmol/L) | 12.1 ± 3.1 | 26.0 ± 6.8* | 49.7 ± 10.9*,** | 66.6 ± 14.2*,**,*** | <0.001 |
| ALT (U/L) | 24.6 ± 6.4 | 36.4 ± 4.6* | 52.1 ± 9.9*,** | 69.0 ± 12.4*,**,*** | <0.001 |
| AST (U/L) | 23.9 ± 6.1 | 33.8 ± 7.7* | 52.9 ± 14.3*,** | 81.4 ± 11.9*,**,*** | <0.001 |
| BNP (pg/ml) | 34.5 ± 9.0 | 68.7 ± 10.3* | 128.5 ± 14.5*,** | 186.8 ± 42.3*,**,*** | <0.001 |
Data are expressed as mean ± SD or as number (percentage).
BMI, body mass index; BSA, body surface area; HR, heart rate; SBP, systolic blood pressure; DBP, diastolic blood pressure; PP, pulse pressure; ALB, Albumin; TBil, total bilirubin; ALT, alanine aminotransferase; AST, aspartate aminotransferase; BNP, brain natriuretic peptide.
*
P < 0.05 vs. CON; **P < 0.05 vs. Child-Pugh A; ,***P < 0.05 vs. Child-Pugh B.