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. 2023 Mar 21;13:35. doi: 10.1186/s13568-023-01539-6

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — The alterations of microbial markers during disease progression. a Alterations of genera overlapped in the LC-associated genera and the HCC-associated genera in Fuzhou samples. b Alterations of LC-associated genera in Fuzhou samples. c Alterations of HCC-associated genera in Fuzhou samples. d Alterations of genera overlapped in the LC-associated genera and the HCC-associated genera in Jilin samples. e Alterations of LC-associated genera in Jilin samples. f Alterations of HCC-associated genera in Jilin samples. g ROC curve of the RF model based on eight genera for discriminating HCC and LC in the combined dataset of Fuzhou and Jilin samples