Fig. 2.

Follow-up magnetic resonance images taken 2 months after disease onset, revealed mottled multiple high-signal areas in the bilateral cerebral white matter on T2-weighted images (A) and diffusion-weighted images (B), and reduced signal on an apparent diffusion coefficient map (C, arrows). The lesions showed high signal intensity on fluid-attenuated inversion recovery images (D). The lesions were distributed predominantly in the watershed area. Reductions in the size and signal of the oval lesion in the splenium of the corpus callosum were observed. T1-weighted images showed diffuse low-signal intensity in the bone marrow (E). The dura mater was thick and enhanced with the gadolinium-based contrast agent (F).