Table 3.
Univariate analysis stratified by smoking in NaIS.
| Non-smoker | Smoker | p value | |
|---|---|---|---|
| Number | 303 | 197 | |
| Age, y.o. | 72.0 (65.0–78.0) | 69.0 (61.0–76.5) | 0.0045 |
| Male | 52 (17.1) | 172 (87.3) | <0.0001 |
| Drinking | 51 (16.8) | 102 (51.8) | <0.0001 |
| Alcohol consumption | 0 (0.0–0.0) | 20.0 (0.0–140.0) | <0.0001 |
| Hypertension | 99 (32.7) | 67 (34.0) | 0.77 |
| Diabetes Mellitus | 16 (5.3) | 14 (7.1) | 0.34 |
| Body mass index | 22.6 (20.2–25.2) | 23.3 (21.2–25.3) | 0.048 |
| Uric acid (mg/dL) | 4.8 (4.0–5.6) | 5.7 (4.7–6.7) | <0.0001 |
| Creatinine (mg/dL) | 0.66 (0.58–0.78) | 0.83 (0.73–0.94) | <0.0001 |
| eGFR (mL/min/1.73m2) | 70.4 (61.4–81.0) | 70.0 (60.0–80.3) | 0.93 |
| LDL cholesterol (mg/dL) | 121.0 (103.0–141.0) | 113.0 (96.5–130.5) | 0.0023 |
| HTLV-1 Ab (CLEIA) | 61 (20.1) | 27 (13.7) | 0.09 |
| Total IgG (mg/dL) | 3826 (3123.4–4455.1) | 3873.5 (3214.2–4659.5) | 0.31 |
| IgG4/total IgG | 0.13 (0.039–0.46) | 0.32 (0.078–0.54) | <0.0001 |
| IgE (ng/mL) | 553.7 (307.8–1020.1) | 826.1 (467.1–1867.2) | <0.0001 |
P-values were established using Pearson’s chi-square test or Wilcoxon’s rank sum test.
Data are median (IQR) or n (%). eGFR, estimated glomerular filtration rate; LDL cholesterol, low-density lipoprotein-cholesterol; HTLV-1, Human T-cell leukemia virus type 1. p < 0.05 was considered statistically significant.