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. 2023 Mar 8;14:1134877. doi: 10.3389/fendo.2023.1134877

Table 5.

Changes in hepatorenal levels in two groups (mean ± SD).

CG IG Ft/Pt Fg/Pg Fi/P i
ALT (U/L) Pre 21.07 ± 10.17 20.50 ± 5.70 0.601/0.443 0.666/0.419 0.827/0.369
Week 12 21.26 ± 10.62 19.03 ± 8.28
0.19 ± 7.59 -1.47 ± 8.18 0.958/0.341
AST (U/L) Pre 18.50 ± 7.03 20.27 ± 6.90 10.674/<0.01 0.131/0.719 3.716/0.061
Week 12 18.10 ± 6.77 17.47 ± 4.25 *
F 0.341 10.421
P 0.563 <0.01
-0.40 ± 4.49 -2.80 ± 5.55† 2.161/0.034
TP (g/L) Pre 71.33 ± 5.06 69.66 ± 4.44 1.331/0.256 10.502/<0.01 6.180/0.017
Week 12 72.24 ± 4.29 67.35 ± 5.42† *
F 1.110 6.718
P 0.298 0.013
0.91 ± 5.60 -2.31 ± 5.70† 2.595/0.011
ALB (g/L) Pre 44.80 ± 3.26 43.72 ± 3.17 5.138/0.029 14.507/<0.01 19.719/<0.01
Week 12 45.31 ± 3.61 41.91 ± 3.47† *
F 2.604 16.283
P 0.114 <0.01
0.50 ± 2.02 -1.81 ± 2.88† 4.236/<0.01
TBIL (µmol/L) Pre 9.69 ± 4.09 10.29 ± 2.28 2.754/0.105 0.033/0.857 1.608/0.212
Week 12 10.82 ± 5.03 10.48 ± 2.75
1.12 ± 4.50 0.19 ± 2.34 1.186/0.240
ALP (U/L) Pre 100.12 ± 21.14 101.10 ± 18.53 26.841/<0.01 0.705/0.406 1.765/0.192
Week 12 94.76 ± 21.80 88.02 ± 17.41 *
F 2.552 14.696
P 0.118 <0.01
-5.36 ± 21.73 -13.07 ± 21.84 1.613/0.111
BUN (mmol/L) Pre 5.75 ± 1.23 5.53 ± 0.82 0.038/0.846 <0.01/0.995 2.053/0.160
Week 12 5.61 ± 1.42 5.76 ± 1.01
-0.15 ± 1.23 0.22 ± 1.24 -1.357/0.179
CREA (µmol/L) Pre 74.06 ± 15.77 75.58 ± 15.23 24.203/<0.01 2.408/0.129 19.456/<0.01
Week 12 73.98 ± 16.06 63.41 ± 13.60† *
F 0.006 26.043
P 0.940 <0.01
-0.08 ± 6.92 -12.17 ± 15.26† 4.626/<0.01
UA (µmol/L) Pre 328.08 ± 70.56 323.93 ± 84.13 0.012/0.913 0.041/0.840 2.777/0.103
Week 12 320.91 ± 69.92 330.83 ± 66.91
-7.16 ± 39.83 6.89 ± 40.35 -1.597/0.114

Ft/Pt , Fg/Pg , and Fi/Pi : two-way repeated measures ANOVA, time effect, group effect, and group. *time interaction;

†: P<0.05 vs. CG; *: P<0.05 vs. Pre; CG, control group; IG, intervention group.