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. 2022 Oct 6;20(4):981–994. doi: 10.1111/iwj.13948

TABLE 3.

Univariate and multivariate regression analysis for risk factors of SSI on training cohort

Univariate Multivariate
OR 95% CI 95% CI P value OR 95% CI 95% CI P value
Sex
Male reference
Female 0.980 0.472 2.037 .957
Age 1.035 0.994 1.077 .092
BMI
<25 reference
≥25 0.790 0.382 1.635 .526
Cardiovascular disease
No reference
Yes 1.092 0.503 2.370 .823
Number of fused vertebrae
1 reference reference
≥2 6.397 1.892 21.629 .003* 9.222 1.500 56.688 .017*
Operative time 1.001 0.998 1.003 .680
Intraoperative blood loss 1.001 0.999 1.002 .285
Intraoperative blood transfusion 1.001 0.999 1.002 .338
Length of the incision 1.145 1.006 1.303 .040*
Duration of drain placement 1.529 1.122 2.082 .007* 1.629 1.066 2.489 .024*
Duration of diabetes (yr)
≤5 reference reference
>5 3.296 1.373 7.912 .008* 6.226 1.655 23.423 .007*
HbA1c 1.151 0.829 1.598 .401
Preoperative blood glucose control scheme .023* .012*
Subcutaneous injection of insulin reference reference
Combined medication 8.250 1.714 39.720 .008* 3.822 .193
Oral hypoglycemic agent 2.667 0.530 13.417 .234 13.183 .022*
Diet therapy 5.508 1.194 25.415 .029* 26.442 .002*
Preoperative MFBG 1.591 1.265 2.001 .000* 1.618 1.098 2.386 .015*
Preoperative FPG‐CV 1.159 1.105 1.216 .000* 1.194 1.106 1.289 .000*
Postoperative MFBG 1.068 0.868 1.313 .536
Postoperative FPG‐CV 1.079 1.042 1.117 .000* 1.063 1.010 1.120 .022*

Note: OR odds ratio, 95% CI 95% confidence interval. *P < .05. *Statistically significant preoperative blood glucose control scheme is multi‐categorical variable, so covariate is generated for analysis.

Abbreviations: FPG‐CV: variation coefficient of fasting plasma glucose; MFBG: mean fasting blood glucose.

*Statistically significant preoperative blood glucose control scheme is multi‐categorical variable, so covariate is generated for analysis.