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. 2022 Nov 15;13(3):1036–1052. doi: 10.1016/j.apsb.2022.11.012

Figure 1.

Figure 1

CDDP protects ApoE–/–LDLR–/– mice against HFD-induced myocardial injury. (A) Mice were assigned to the groups and received the indicated treatment. After 16-week treatment, mice were conducted the following assays. (B, C) Aortic en face lesions were determined by oil red O staining with quantitative analysis of lesion areas. (D, E) The representative pictures of mouse ECG and echocardiographic test. (F) Ejection fraction and fractional shortening were calculated based on echocardiographic test. The data are shown as mean ± SEM. ∗∗∗P < 0.001 vs. Ctrl; #P < 0.05, ###P < 0.001 vs. LST; ns: not significantly different between indicated groups. n = 5–9 mice/group. ECG: electrocardiograms.