Table 1.
Demographic and Clinical Characteristics of Patients (n = 123) With Superior Sulcus Tumors, Treated With Chemoradiotherapy and Surgery Between 2002 and 2017
| Demographic and Clinical Characteristics | n | % |
|---|---|---|
| Number of patients | 123 | |
| Sex (male:female) | 77 vs. 46 | |
| Age (mean, SD) | 56.6 (9.4) | |
| Mediastinal nodal evaluation | ||
| EUS | 16 | 13.0 |
| EBUS | 24 | 19.5 |
| Mediastinal | 15 | 12.2 |
| Radiotherapy | ||
| 39–49 Gy | 27 | 22.0 |
| 50–59 Gy | 66 | 53.7 |
| 60–66 Gy | 30 | 24.4 |
| Reduction in dose radiotherapy | ||
| 0% | 118 | 95.9 |
| 25% | 4 | 3.3 |
| 50% | 1 | 0.8 |
| Tumor characteristics | ||
| Histopathology | ||
| NSCLC-NOS | 51 | 41.5 |
| Adenocarcinoma | 42 | 34.1 |
| Squamous cell carcinoma | 30 | 24.4 |
| Laterality | ||
| Right | 92 | 74.8 |
| Left | 31 | 25.2 |
| Clinical T status | ||
| T3 | 76 | 61.8 |
| T4 | 47 | 38.2 |
| cTNM seventh edition (2010–2018) | ||
| IIb | 46 | 37.4 |
| IIIa | 70 | 56.9 |
| IIIB | 7 | 5.7 |
| Clinical nodal status | ||
| No lymph nodes | 83 | 67.5 |
| Hilar | 19 | 15.4 |
| Mediastinal | 20 | 16.3 |
| Supraclavicular | 1 | 0.8 |
| Surgical characteristics | ||
| Surgical approach | ||
| Anterior | 12 | 9.8 |
| Posterolateral | 110 | 89.4 |
| Combined | 1 | 0.8 |
| Type of pulmonary resection | ||
| Lobectomy | 108 | 87.8 |
| Bilobectomy | 2 | 1.6 |
| Wedge resection | 6 | 4.9 |
| Lobectomy and wedge | 3 | 2.4 |
| Segmentectomy | 2 | 1.6 |
| Sleeve | 2 | 1.6 |
| Extended resection | ||
| Subclavian artery | 2 | 1.6 |
| Bronchial sleeve | 1 | 0.8 |
| Combined bronchial/arterial sleeve | 1 | 0.8 |
| Complete vertebra(e) | 6 | 4.9 |
| Partial vertebra(e) | 4 | 3.2 |
| Partial sternectomy + partial vertebra(e) | 1 | 0.8 |
| Partial sternectomy + subclavian artery | 2 | 1.6 |
| Resection chest wall (number of ribs) | ||
| None | 1 | 0.8 |
| One | 5 | 4.1 |
| Two | 16 | 13.0 |
| Three | 42 | 34.1 |
| Four | 51 | 41.5 |
| Five | 8 | 6.5 |
| Pathology characteristics | ||
| Resection margin | ||
| R0 | 114 | 92.7 |
| R1 | 9 | 7.3 |
| Pathologic response rate | ||
| Major (complete) response | 84 (52) | 68.3 (42.3) |
| Nonmajor response | 39 | 31.7 |
| pTNM (seventh edition 2007–2018) | ||
| 0 | 52 | 42.3 |
| Ia | 23 | 18.7 |
| IIa | 2 | 1.6 |
| IIb | 37 | 30.1 |
| IIIa | 9 | 7.3 |
cTNM, clinical TNM; EBUS, endobronchial ultrasound; EUS, endoscopic ultrasound; NSCLC-NOS, NSCLC not otherwise specified; pTNM, pathologic TNM.