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. 2023 Mar 8;13:1094644. doi: 10.3389/fimmu.2022.1094644

Table 5.

TMPRSS2 and cytometry comparisons in COVID-19 aggressiveness.

Mild vs. Severe
Variants OR 95% CI p-value Omnibus test R2 Nagelkerke
(Step/Block/Model) *
TMPRSS2_rs2070788_Dom 3.2 1.07-9.51 0.036 0.005 0.201
CD45- 0.3 0.10-0.85 0.025
TMPRSS2_rs2070788_Dom 5.28 1.57-17.68 0.007 0.002 0.228
T-Mo CD163+/CD206- 4.34 1.34-13.96 0.014
TMPRSS2_rs2070788_Dom 4.42 1.38-14.10 0.012 0.001 0.242
CD14dim/CD33+ 0.22 0.07-0.679 0.008

*All explanatory variables were added in one block and therefore have only one step. This means that the p-values are the same for the step, block, and model.

Dom, dominant model.

In bold statistically significant values.