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. Author manuscript; available in PMC: 2023 Mar 22.
Published in final edited form as: Nat Rev Dis Primers. 2021 Oct 7;7(1):73. doi: 10.1038/s41572-021-00307-9

Figure 4. Manifestations of LCH.

Figure 4.

A. Erythematous, scaly LCH rash; B. Multiple lytic skull lesions (arrows) in a patient with LCH; C. PET scan showing involvement of skull base, occiput, left fifth rib, left iliac bone, and left hemisacrum. Although the intense uptake in long bones is physiological, the scan shows hypermetabolic splenomegaly and bilateral cervical/upper abdominal lymphadenopathy.); D Pulmonary cysts and nodules (arrows) from LCH; E. Brain MRI with intense T2 signal in the dentate nuclei characteristic of neurodegenerative LCH (arrow).