TABLE 2.
Clinicopathologic Risk Factors Based on Surgical Pathology
| Pathology | No. (%) | <1 Copy/mL | 1–100 Copies/mL | >100 Copies/mL |
|---|---|---|---|---|
|
| ||||
| Distant metastasis | 1 (3) | 0 | 0 | 1 |
| Gross positive margins | 1 (3) | 0 | 0 | 1 |
| Gross ENE | 1 (3) | 0 | 0 | 1 |
| ENE >1 mm | 4 (12) | 0 | 3 | 1 |
| Focal positive margins | 3 (9) | 1 | 2 | 0 |
| Close margins | 4 (12) | 3 | 1 | 0 |
| PNI | 6 (18) | 3 | 2 | 1 |
| LVI | 8 (24) | 4 | 2 | 2 |
| ENE ≤1 mm | 2 (6) | 1 | 1 | 0 |
| Lymph nodes | ||||
| 0 | 4 (12) | 4 | 0 | 0 |
| 1 | 17 (51) | 10 | 7 | 0 |
| 2 | 7 (21) | 6 | 1 | 0 |
| >2 | 4 (12) | 1 | 2 | 1 |
ENE, extranodal extension; LVI, lymphovascular invasion; PNI, perineural invasion.