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. 2023 Mar 10;19(3):e1011214. doi: 10.1371/journal.ppat.1011214

Table 1. Mutations detected in the CNS of a ferret infected with virus of the H5N1 subtype.

Three substitutions were found in common between the cerebellum (CL) and cerebrospinal fluid (CSF). REF refers to the nucleotide reference; ALT to the nucleotide alternative variant; REF-AA amino acid reference; ALT-AA to substitution. Sequencing was done using MySeq Illumina platform.

Sample Segment Position REF ALT REF-AA ALT-AA Frequency Coverage
CL PB1 554 A G E G 0.994 5011
CL PB1 1978 G A A T 0.662 4683
CL NP 402 T G I M 0.991 7980
CSF PB1 554 A G E G 0.993 7934
CSF PB1 1978 G A A T 0.534 7930
CSF NP 402 T G I M 0.992 7986